Table 3.
Corneal sensitivity thresholds and corneal nerve and LC parameters according to disease activity in patients with rheumatoid arthritis.
| DAS28-ESR ≤ 3.2 (n = 25) |
DAS28-ESR > 3.2 (n = 25) |
P value | |
|---|---|---|---|
| Central corneal sensitivity (cm), median (IQR) | 6.0 (5.5–6.0) | 5.5 (5.5–6.0) | 0.491a |
| CNFD (no./mm2), mean ± SD | 33.1 ± 6.8 | 28.6 ± 5.9 | 0.016b |
| CNBD (no./mm2), median (IQR) | 50.0 (32.3–62.5) | 35.4 (25.0–56.3) | 0.103a |
| CNFL (mm/mm2), mean ± SD | 19.8 ± 3.5 | 17.3 ± 4.2 | 0.028b |
| LC density (no./mm2), median (IQR) | 22.9 (4.2–54.2) | 47.9 (22.9–79.2) | 0.079a |
| Mature LC density (no./mm2), median (IQR) | 4.2 (0–13.5) | 8.3 (0–16.7) | 0.403a |
| Immature LC density (no./mm2), median (IQR) | 20.8 (4.2–38.5) | 35.5 (16.5–65.6) | 0.069a |
CNFD corneal nerve fibre density, CNBD corneal nerve branch density, CNFL corneal nerve fibre length, LC Langerhans cell.
aMann–Whitney U-test.
bIndependent samples t-test.