Table 2.

OCTA machine and parameters of included studies^a.

Author, Country, Year	OCTA machine	OCTA parameters assessed within macula	Macular scan diameter (mm)
Kwapong et al., China, 2018	Optovue	Vessel density (%) of SVP, DVP and whole retinal capillary plexus (Ø 0.6–2.5 mm) and FAZ (mm2)	2.5
Berkowitz et al., USA, 2020	Optovue	FAZ (mm2)	6
Rascunà et al., Italy, 2020	Optovue	Vessel density (%) of SVP, DVP, outer retinal layer (whole [3 mm diameter circle], fovea [1 mm diameter circle] and parafovea [Ø 1-3 mm])	3 and 4.5
Shi et al., China, 2020	Optovue	Vessel density (%) and skeleton density (%) of SVP and DVP (Ø 0.6–2.5 mm)	2.5
Zou et al., China, 2020	Zeiss	Perfusion density (%) and vessel length density (mm) of SVP (1 mm, 3 mm and 6 mm diameter circles, Ø 1-3 mm and Ø 3-6 mm) and FAZ (mm2)	6
Robbins et al., USA, 2020	Zeiss	Perfusion density (%) and vessel density (/mm) of SVP (whole [6 mm diameter circle], parafovea [Ø 1-3 mm] and perifovea [Ø 3-6 mm]) and FAZ (mm2)	6
Zhang et al., China, 2021	SVision	Flow density (mm2) and flow ratio (%) of SVP and DVP (whole [3 mm and 6 mm diameter circles] and fovea [1 mm diameter circle])	6
Murueta-Goyena et al., Spain, 2021	Heidelberg Engineering	Perfusion density (%), skeleton density (1/mm) and fractal dimension (Dbox) of SVP and DVP (whole [2.5 mm diameter circle], fovea [1 mm circle diameter] and parafovea [Ø 1-2.5 mm]) and FAZ (mm2)	2.5
Zhou et al., China, 2021	Zeiss	Vessel density (/mm) of SVP (whole [6 mm diameter circle], fovea [1 mm circle diameter], parafovea [Ø 1-3 mm] and perifovea [Ø 3-6 mm]) and FAZ (mm2)	6 and 3

Meta-analyzed metrics of each study appear in bold.

^aDVP deep vascular plexus, FAZ Foveal Avascular Zone (mm²), SVP superficial vascular plexus, Ø ring around fovea.