Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Genetic alterations in OSCC. Genetic alteration in the TP53/RB, p16/Cyclin D1/Rb, EGFR, Wnt/β-catenin, JAK/STAT, NOTCH, PI3K/AKT/mTOR, MET, RAS/RAF/MASK signaling pathways contribute to OSCC progression. EGFR epidermal growth factor receptors, JAK Janus-activated kinase, MAPK mitogen-activated protein kinase, OSCC oral squamous cell carcinoma, RB retinoblastoma, Rb retinoblastoma tumor suppressor protein, STAT signal transducer and activator of the transcription, TP53 tumor protein p53
