Figure 2.

Acetate facilitates astrocytic GABA synthesis in AD-like conditions. (A) Schematic diagram of astrocytic GABA-synthetic pathway. (B–D) The level of putrescine, N-acetyl-GABA and GABA analysed by LC-MS. (E) Schematic diagram of sniffer patch to record GABA current. (F) Representative traces of Ca²⁺ signal (top) and GABA current (bottom). Diamonds indicate the time point of poking the astrocyte. (G) Quantification of poking-induced GABA current. Mean ± SEM. Significance was assessed by one-way ANOVA with Tukey.