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. 2023 Aug 14;33(3):407–426. doi: 10.1016/j.zemedi.2023.04.007

Figure 6.

Figure 6

Fibrosis: (A) and (B) Representative low and high magnification images of Masson trichrome-stained tumor cross-sections of PC3 xenograft, respectively. Treatments condition included ultrasound-stimulated microbubbles (USMB; 1%), multi-fraction radiation (XRT), and combined (USMB + XRT) treatments. Animals were administered with USMB treatments twice weekly, and for XRT only and combined treatments, animals were exposed to five fractions/week at 2 Gy each over 3 weeks (BED10 = 30 Gy). Increased fibrotic tissues were observed by the third week in tumors receiving combined treatment. The scale bar represents 2 mm for low-magnification images and 50 μm for high-magnification images. From [80].