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. 2023 Aug 14;33(3):407–426. doi: 10.1016/j.zemedi.2023.04.007

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© 2023 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Pilot data from phase I study of ultrasound-microbubble stimulation in breast cancer. Top left: Clinical view of treated lesions before treatment (red ellipse) with MRg-FUS + MB + XRT for radiation enhancement. Ellipse is 5.0 cm in the largest dimension. Top right: Clinical view of lesions indicating diminished lesion sizes 4 weeks after treatment with MRg-FUS + MB. Bottom left: MRI plan indicating where focused ultrasound was directed for microbubble stimulation. Bottom right: MRI plan indicating where radiation was directed for treatment. Treatment with radiation was administered immediately after MRg-FUS + MB therapy From [84].