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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Biol Psychiatry. 2023 Feb 1;94(5):393–404. doi: 10.1016/j.biopsych.2023.01.018

Figure 2.

Figure 2.

A, Relative c-fos expression in high- (HD) and low-drinking (LD) mice during acute (24h) alcohol withdrawal and following a 1h alcohol reaccess period. C-fos-positive cell counts for each region are represented as the percent change relative to LD mice during withdrawal. Regions are grouped by anatomical subdivision according to the Allen Brain Atlas. * denotes a significant main effect of drinking history; % denotes a significant main effect of reaccess EtOH drinking; and # denotes a significant interaction between drinking history and alcohol reaccess (2-way ANOVA with FDR correction for multiple comparisons). Post-hoc test p-values are available in Table S3.