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. 2023 Sep 22;17:11795549231199915. doi: 10.1177/11795549231199915

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — Potential role of SPAG5 in tumor immunosuppression. Correlation between SPAG5 Expression and Tumor Immune Infiltration in LUAD. (A) The correlation between SPAG5 expression and tumor immune infiltration was systematically analyzed using the TIMER2.0 website. The scatter plots illustrate the correlation between SPAG5 expression and the infiltration levels of 16 distinct immune cell types in LUAD. The X-axis represents the level of immune infiltration, whereas the Y-axis denotes the expression level of SPAG5. (B) The TIMER2.0 website was employed to investigate the correlation between SPAG5 expression and the specific inhibitory immune checkpoint as indicated. LUAD indicates lung adenocarcinoma; SPAG5, sperm-associated antigen 5; TIMER, tumor immune estimation resource.