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. 2023 Sep 21;4(9):1345–1361. doi: 10.1038/s43018-023-00630-y

Extended Data Fig. 9. Anti-tumor activity of vepafestinib in comparison with selpercatinib or pralsetinib.

Extended Data Fig. 9

Animals bearing Ba/F3-KIF5B::RETWT allograft tumors were treated with (a) vehicle, vepafestinib or selpercatinib or with (b) vehicle, vepafestinib or pralsetinib. Data shown is the mean ± SEM (n = 5 per group).* P < 0.05 compared with the control group by Dunnett test. Tests were two-sided. Drugs or vehicle were administrated orally at the indicated doses, twice daily (BID) for 14 days (Day 1-14) after grouping.

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