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Adverse events during treatment in 68 patients.
| Adverse events | Grade 1-2 | Grade 3 | ||||
|---|---|---|---|---|---|---|
| Control group | Study group | Control group | Study group | Total (%) | ||
| Oral ulcers | 3 | 2 | 0 | 0 | 5 (7.6%) | |
| Rash | 8 | 7 | 0 | 0 | 15 (22.1%) | |
| Diarrhea | 1 | 4 | 1 | 0 | 6 (8.8%) | |
| Nausea | 1 | 3 | 2 | 0 | 6 (8.8%) | |
| Myelosuppression | 3 | 9 | 0 | 7 | 19 (27.9%) | |
| Hepatotoxicity | 0 | 6 | 0 | 0 | 6 (8.8%) | |
| increased CK | 5 | 7 | 0 | 0 | 12 (17.6%) | |
| Fatigue | 1 | 2 | 0 | 0 | 3 (4.4%) | |
| Decreased appetite | 1 | 4 | 0 | 0 | 5 (7.4%) | |
