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. 2023 Sep 11;14:1242909. doi: 10.3389/fimmu.2023.1242909

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Copyright © 2023 Xu, Zhang, Zhao, Wang, Zhang, Li, Zhu and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of communication between Treg cell and other cells in pancreatic cancer microenvironment. (A) Integrated map of the overall communication intensity of each cell in pancreatic cancer tissues. (B) Show the overall communication intensity of each cell in pancreatic cancer tissues. (C, D) Treg cells are important signaling pathways involved as signal senders and receivers. (E, F) Treg cells are important ligands-receptors in important signaling pathways involved in signal senders and receivers. (G) Overall strength of Treg cells as signal receivers (vertical axis) and transmitters (horizontal axis). (H, I) Treg cells are important ligand-receptors in the five most important signaling pathways involved by signal senders and receivers. (J) Intensity demonstration of all cells as signal receivers and transmitters in different pathways.