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. 2023 Sep 11;14:1233807. doi: 10.3389/fimmu.2023.1233807

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Copyright © 2023 Fu, Liu, Li, Wei, Alam, Deng, Li, Wu, He, Hou, Xia, Wang, Wang, Bai, Xu, Li, Wu, Liu and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CRP deficiency has no remarkable impact on angiogenesis in aneurysmal aortas. Frozen sections were prepared from the aortas of non-aneurysmal normal (upper left) and aneurysmal (wild type: upper right; CRP^-/-: lower left) mice (n=10-11 mice per group) and stained with an anti-CD31 antibody to assess aneurysmal angiogenesis. Lower right panel: angiogenesis in wild and CRP^-/- aneurysmal mouse aortas was quantitated as the number of CD31-positive neovessels per ACS. Data are mean ± standard deviation. Student’s t tests, no significant difference between two groups.