Figure 7.

Progression-related protein classifier of UTUC patients

(A) Volcano plot of proteins correlated with PFS.

(B) Pathways enriched for proteins significantly positively or negatively correlated with PFS.

(C) Forest plots of the univariate Cox hazard model for PFS.

(D) AUC was 0.742, 0.816, and 0.877 at 1, 3, and 5 years, respectively, in UTUC discovery cohort.

(E) Calibration curves of nomograms between predicted and observed 1-, 3-, and 5-year PFS in discovery UTUC cohort.

(F) AUC was 0.812, 0.88, and 0.905 at 1, 3, and 5 years, respectively, in validation cohort using PRM assays.