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. 2023 Aug 30;4(9):101174. doi: 10.1016/j.xcrm.2023.101174

Figure 3.

Figure 3

Result summary of MR and colocalization analysis on the associations between diabetes-related proteins and the risk of diabetic complications

(A–C) The gray squares in (A) indicate missing data. Full name of proteins: ABO, histo-blood group ABO system transferase; ANGPTL4, angiopoietin-related protein 4; ARG1, arginase-1; ASIP, Agouti-signaling protein; BDH2, 3-hydroxybutyrate dehydrogenase type 2; BOC, brother of CDO; CTRB2, chymotrypsinogen B2; DDR1, epithelial discoidin domain-containing receptor 1; GALNT3, polypeptide N-acetylgalactosaminyltransferase 3; GCKR, glucokinase regulatory protein; HP, haptoglobin; HSPA1A, heat shock 70 kDa protein 1A; HSPA1B, heat shock 70 kDa protein 1B; HYOU1, hypoxia up-regulated protein 1; INHBB, inhibin beta B chain; KIAA1161, uncharacterized family 31 glucosidase KIAA1161; MPPED2, metallophosphoesterase MPPED2; MSRA, mitochondrial peptide methionine sulfoxide reductase; NCAN, neurocan core protein; NUCB2, nucleobindin-2; PCSK7, proprotein convertase subtilisin/kexin type 7; PLEKHA1, pleckstrin homology domain-containing family A member 1; PTPN9, tyrosine-protein phosphatase non-receptor type 9; RAB1A, Ras-related protein Rab-1A; ROBO2, roundabout homolog 2; RTBDN, retbindin; SF3B4, splicing factor 3B subunit 4; SNUPN, snurportin-1; TBCE, tubulin-specific chaperone E; TIGAR, fructose-2,6-bisphosphatase TIGAR; TNFSF13, tumor necrosis factor ligand superfamily member 13; TP53, cellular tumor antigen p53; TYRO3, tyrosine-protein kinase receptor TYRO3.