REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
BV786 Mouse anti-Human CD45	BD Horizon	Cat# 563716; RRID:AB_2716864
APC-H7 Mouse anti-Human CD4	BD Pharmingen	Cat# 560158; RRID:AB_1645478
PerCP-Cy5.5 Mouse anti-Human CD8	BD Pharmingen	Cat# 560662; RRID:AB_1727513
APC Mouse anti-Human CD8	BD Pharmingen	Cat# 555369; RRID:AB_398595
PE-Cy7 Mouse anti-Human CD3	BD Pharmingen	Cat# 563423; RRID:AB_2738196
BV510 Mouse anti-Human CD19	BD Pharmingen	Cat# 562947; RRID:AB_2737912
PE-CF594 Mouse Anti-human CD45RO BD	BD Biosciences	Cat# 562299; RRID:AB_11154398
BV421 Mouse Anti-human CD14	BD Biosciences	Cat# 558121; RRID:AB_397041
PE-Cy7 Mouse Anti-human CD45RA	BD Biosciences	Cat# 337167; RRID:AB_647424
PE Mouse anti-Mouse CD45.1	BD Pharmingen	Cat# 561872; RRID:AB_395044
PE-Cy5 Mouse anti-Human CD62L	BD Pharmingen	Cat# 555545; RRID:AB_395929
BV421 Mouse anti-Human CD44	BD Horizon	Cat# 562890; RRID:AB_2737869
PE-Cy5 Mouse anti-Human CD45	BD Pharmingen	Cat# 555484; RRID:AB_395876
PE Rat anti-Mouse LY6C + LY6G (Gr-1)	BD Pharmingen	Cat# 553128; RRID:AB_394644
Alexa Fluor 488 Mouse anti-Human CD197 (CCR7)	BioLegend	Cat# 353205; RRID:AB_10916389
BV711 Mouse anti-Human CD27	BD Horizon	Cat# 563167; RRID:AB_2738042
PE Mouse anti-Human CD3	BD Pharmingen	Cat# 555340; RRID:AB_395746
APC Mouse anti-Human CD4	BD Pharmingen	Cat# 555349; RRID:AB_398593
Bacterial and virus strains
OneShot™ Stbl3™ chemically-competent E.coli	ThermoFisher Scientific	Cat# C737303
Biological samples
Cord Blood CD34+ Stem/Progenitor cells	Lonza	Cat# 2C-101
PBMC samples from people living with HIV on ART	The Alfred Hospital and The Avenue Hospital, Melbourne, AUS	N/A
Chemicals, peptides, and recombinant proteins
Venetoclax	Active Biochem or SelleckChem	Cat# A-1231 or S8048, respectively
S63845	MedChemExpress	Cat# HY-100741
Tenofovir disoproxil fumarate	Gilead Sciences	Eviplera
Emtricitabine	Gilead Sciences	Eviplera
Rilpivirine	Gilead Sciences	Eviplera
Raltegravir (for in vivo use)	Merck	Isentress
Efavirenz	NIH HIV Reagent Program	Cat# HRP-4624, https://www.hivreagentprogram.org/Catalog/HRPAntimicrobialCompoundsandOtherChemicals/HRP-4624.aspx
Zidovudine	NIH HIV Reagent Program	Cat# ARP-3485, https://www.hivreagentprogram.org/Catalog/HRPAntimicrobialCompoundsandOtherChemicals/ARP-3485.aspx
Raltegravir (for ex vivo use)	NIH HIV Reagent Program	Cat# HRP-11680, https://www.hivreagentprogram.org/Catalog/HRPAntimicrobialCompoundsandOtherChemicals/HRP-11680.aspx
Phorbol-12-myristate-13-acetate (PMA)	Sigma	Cat# P8139
Ionomycin calcium salt	Sigma	Cat# I0634
Critical commercial assays
Invisorb Virus RNA HTS 96 Kit/C	Stratec	Cat# 7043300300
SYBR™ Green RNA-to-CT™ 1-step Kit	ThermoFisher Scientific	Cat# 4389986
HIV-1 p24 ELISA kit	Jomar Life Research	Cat# XB-1000
AllPrep DNA/RNA Mini kit	Qiagen	Cat# 80204
TruSeq RNA Library Prep kit v2	Illumina	Cat# RS-122-2001
Qubit™ DNA BR assay kit	ThermoFisher Scientific	Cat# Q32850
LIVE/DEAD™Fixable Violet Dead Cell Stain kit	ThermoFisher Scientific	Cat# L34955
QIAamp DNA Mini Kit (250)	Qiagen	Cat# 51306
EasySep™ Human CD4+ T cell Isolation kit	StemCell Technologies	Cat# 17952
Deposited data
RNA-Seq data at Gene Expression Omnibus	Gene Expression Omnimus (GEO)	GEO: GSE222783
Original R script used in the processing and analysis of the RNA-Seq data	GitHub	https://github.com/sheerind-wehi/venetoclax_RNA_seq/blob/main/QC%20%26%20DGE%20analysis.Rmd
Experimental models: Cell lines
HEK293T cells	Pellegrini Lab, The Walter and Eliza Hall Institute of Medical Research, Melbourne, AUS	N/A
Experimental models: Organisms/strains
NOD.Cg-PrkdcscidIl2rgtm1Wjl/Sz mice (NSG)	The Jackson Laboratory	Strain# 005557
Oligonucleotides
HIV-1 Gag forward primer: AAC ACC ATG CTA AAC ACA GTG G	Integrated DNA Technologies	N/A
HIV-1 Gag reverse primer: GCT TCC TCA TTG ATG GTC TCT T	Integrated DNA Technologies	N/A
Recombinant DNA
HIV-1, strain JR-CSF infectious molecular clone (pYK-JRCSF)	NIH HIV Reagent Program	Cat# ARP-2708
Software and algorithms
BD FACSDiva v9.0	BD Biosciences	https://www.bdbiosciences.com/enau/products/software
FlowJo v10	BD	https://www.flowjo.com/solutions/flowjo/downloads
Prism 9	GraphPad	https://www.graphpad.com/scientific-software/prism/
Limma	Ref. 71	v3.47.9
EdgeR	Ref. 72	v3.33.2
Rsubread	Ref. 69	v2.4.2
Featurecounts	Ref. 70	N/A