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. 2023 Jun;33(6):839–856. doi: 10.1101/gr.276765.122

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© 2023 Resztak et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 2. — Identification of differentially expressed genes (DEGs). (A) Heatmap of log₂ fold change (LFC) of 6571 DEGs (column) across 16 conditions (four contrasts × four cell types; row). (B) Heatmap of Spearman's correlation of LFC across 16 conditions (four cell types × four contrasts). (C–F) Pathway analysis across cell types and treatment conditions for enrichment in DEG (top) and boxplot for average pathway score (bottom) for four pathways: (C) type I interferon (IFN) signaling, (D) coronavirus disease (COVID-19), (E) glucocorticoid stimulus, and (F) asthma.