TABLE 1.
Overview of cohorts.
| ABCD | ABCD matched case‐control | Oregon‐ADHD‐1000 | |
|---|---|---|---|
| Total N | 11,867 | 1620 | 1449 |
| Age (years) | 9.9 (0.6) | 9.9 (0.6) | 9.4 (1.6) |
| % Female | 47.8%* | 31.3%* | 39.1% |
| N with genotypes | 10,497 | 1427 | 770 |
| % White, European | 46.9% (N = 5562) | 45% (N = 732) | 42.0% (N = 609) |
| % Hispanic/Latino | 9.4% (N = 1110) | NA | NA |
| % Black/African‐American | 12.0% (N = 1423) | NA | NA |
| % ADHD cases | 4.5% (N = 540)* | 33.3% (N = 540)* | 49.8% (N = 721; missing = 31) |
| Total ADHD symptoms T‐score | 53.2 (5.6)* | 56.4 (8.8)* | 61.5 (16.4) |
| Family income | Median = $75,000–$99,999* | Median = $75,000–$99,999* | Median = $50,000–$74,999 |
| Family conflict | 2.54 (2.0) | 2.71 (2.0) | NA |
| Negative sentiment | NA | NA | 0 (0.95) |
| Lead risk | 5.1 (3.1)* | 5.00 (3.1) | 4.36 (2.9) |
| NO2 exposure | 18.6 (5.8)* | 18.5 (5.7)* | 17.4 (2.4) |
| PM2.5 exposure | 7.7 (1.6)* | 7.6 (1.4)* | 7.8 (1.4) |
| ADI | 94.7 (21.1)* | 94.8 (21.8)* | 90.5 (12.8) |
Note: The mean and standard deviation (in parentheses) are reported unless otherwise specified. An asterisk (*) indicates a significant difference in distribution compared to the Oregon‐ADHD‐1000.
Abbreviations: ABCD, Adolescent Brain Cognitive Development Study; ADHD, attention‐deficit/hyperactivity disorder; ADI, area deprivation index.