Table 5.
Detailed characteristics of patients with adverse events
| Patient’s sex, Male/Female; Age, years | Clinical presentation | Indication for CDMT treatment | PE risk category | Adverse event | |
|---|---|---|---|---|---|
| 1 | Female; 53 | obstructive shock, cardiac arrest with ongoing CPR, intubated | Unsuccessful ST |
HR | PE-related death during CDMT |
| 2 | Female, 44 | Sudden cardiac arrest, witnessed CPR > 1 h during CDMT, intubated, ECMO delivery | Unsuccessful ST |
HR | Death within 48 h due to post-traumatic brain injury |
| 3 | Male, 50 | Sudden cardiac arrest, CPR > 1 h during CDMT, severe COVID-19 infection, ECMO delivery | Unsuccessful ST |
HR | multiorgan failure—COVID-19 progression |
| 4 | Female, 59 | Syncope, obstructive shock, CPR during CDMT ECMO delivery | Unsuccessful ST |
HR | PE-related death within 48 h |
| 5 | Male, 64 | Syncope, obstructive shock, | Unsuccessful ST |
HR | PE-related death within 48 h |
| 6 | Male, 70 | Obstructive shock | Unsuccessful ST |
HR | PE-related death within 48 h |
| 7 | Female, 84 | Presyncope, respiratory failure, ovarian cancer | Relative contraindications to ST | IHR | Death within 30 days due to ovarian cancer |
| 8 | Female, 48 | Presyncope, respiratory failure, ovarian cancer | Relative contraindications to ST | IHR | Death within 30 days due to ovarian cancer |
| 9 | Female, 53 | Presyncope, respiratory failure, 24 h after haemorrhagic stroke treatment | Absolute contraindications to ST | HR | Multiorgan failure |
| 10 | Male, 44 | Obstructive shock | Unsuccessful ST |
HR | Major bleeding- access-site haematoma BARC 3a |
| 10 | Female, 47 | Obstructive shock | Unsuccessful ST |
HR | Major bleeding- access-site haematoma BARC 3a |
| 11 | Female, 63 | Sudden cardiac arrest, witnessed CPR > 1 h during CDMT, intubated, ECMO delivery | Relative contraindications to ST | HR | Pulmonary artery injury during CDMT |
| 12 | Male, 48 | Obstructive shock | Absolute contraindications to thrombolysis | HR | Pulmonary artery injury during CDMT |
| 13 | Female, 60 | Presyncope, respiratory failure, cervical cancer | no improvement on low-molecular-weight heparin | IHR | Clinical deterioration during transfer on cath lab table before CDMT |
| 14 | Female, 59 | Syncope, obstructive shock, | Unsuccessful ST |
HR | Sustained ventricular tachycardia when passing through RV outflow tract |
Abbreviations: See Table 1; BARC, Bleeding Academic Consortium Research; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation, ST, systemic thrombolysis.