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. 2023 Aug 15;35(10):2029–2037. doi: 10.1007/s40520-023-02521-9

Table 1.

Adjusted association between NF-L and sarcopenic determinants

Dependent variable Handgrip strength SMI SPPB score Gait Speed Time up and go
Rpartial p-value Rpartial p-value Rpartial p-value Rpartial p-value Rpartial p-value
Age (years)  − 0.2644  < 0.0001***  − 0.0095 0.8493  − 0.2425  < 0.0001***  − 0.1884 0.0001*** 0.0992 0.0536
Sexe  − 0.7641  < 0.0001***  − 0.7359  < 0.0001***  − 0.2267  < 0.0001***  − 0.2152  < 0.0001*** 0.1696 0.0009***
Number of drugs  − 0.1571 0.0016**  − 0.0762 0.1265  − 0.2012  < 0.0001***  − 0.1799 0.0003*** 0.1663 0.0012**
Number of concomitant diseases  − 0.01358 0.7861 0.0357 0.4747  − 0.1687 0.0007***  − 0.1192 0.0169*** 0.1093 0.033*
MMSE 0.07393 0.139 0.0815 0.1022 0.2071  < 0.0001***  − 0.1639 0.001***  − 0.1331 0.0095**
Body mass index (kg/m2) 0.04933 0.3238 0.6699  < 0.0001***  − 0.188 0.0001***  − 0.1946 0.001*** 0.0709 0.1682
log NF-L (pg/mL)  − 0.1247 0.123*  − 0.1095 0.0279*  − 0.1747 0.0004***  − 0.2011  < 0.0001*** 0.0097 0.8514