. 2023 Jul 12;5(11):100840. doi: 10.1016/j.jhepr.2023.100840

Table 2.

Pre- and post-transplant outcomes associated with pretransplant liver frailty index

	Pretransplant liver frailty index
Variables	HR/β-coefficient/OR	95% CI	p value
Pretransplant

Death/delisting for sickness
Univariable	HR = 1.66	0.49-5.68	0.419
Multivariable^∗	HR = 1.48	0.36-6.00	0.586
Post-transplant

Length of intensive care unit stay
Univariable	β = 1.24	0.70-1.78	<0.001
Multivariable^∗	β = 0.85	0.26-1.44	0.005
Length of transplant hospitalization
Univariable	β = 1.69	0.47-2.91	0.007
Multivariable^∗∗	—	—	—
Early (<30 days) post-transplant complications
Univariable	OR = 2.05	1.29-3.26	0.002
Multivariable^∗	—	—	—
Severe (≥ grade IIIA) early post-transplant complications¹⁴
Univariable	OR = 1.38	0.80-2.38	0.251
Multivariable^∗	OR = 1.31	0.75-2.31	0.345
Late (30-90days) post-transplant complications
Univariable	OR = 1.85	1.13-3.03	0.014
Multivariable^∗	OR = 2.60	1.47-4.59	0.001
Retransplant within 6 months post-transplant
Univariable	OR = 1.96	0.89-4.31	0.095
Multivariable^∗∗	—	—	—
Cardiovascular events within 6 months post-transplant
Univariable	OR = 1.69	0.70-4.10	0.243
Multivariable^∗∗	—	—
Death within 6 months post-transplant
Univariable	HR = 1.14	0.54-2.42	0.730
Multivariable^∗∗	—	—	—

Results from Cox regression (HR), linear regression (β coefficient) and logistic regression (OR), 95% CI and p value. Values in bold denote statistically significant results (p <0.05). HR, hazard ratio; OR, odds ratio.

^∗

Multivariable adjustment for covariables associated with frailty status in univariable analysis.

^∗∗

Results from univariable models concluded there were no significant variables to adjust for in multivariable analysis.