Table 3.
Observed HAMD scores | Moderating effect of baseline HAMD score | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Post-treatment | Follow-up | Post-treatment | |||||||||||||
Combined | Antidepressants | Combined | Antidepressants | ||||||||||||
Study | Mean | s.d. | n | Mean | s.d. | n | Mean | s.d. | n | Mean | s.d. | n | d | 95% CI | p |
Burnand et al. (2002) | 8.94 | 7.00 | 35 | 9.67 | 7.34 | 39 | – | – | – | – | – | – | −0.544 | −0.828 to −0.260 | <0.001 |
de Jonghe et al. (2001) | 10.53 | 6.70 | 59 | 13.64 | 8.44 | 33 | 6.78 | 6.88 | 60 | 9.32 | 9.15 | 37 | −0.644 | −0.816 to −0.472 | <0.001 |
López Rodríguez et al. (2004) | 0.10 | 0.32 | 10 | 0.30 | 0.48 | 10 | 0.00 | 0.00 | 10 | 0.30 | 0.48 | 10 | −0.329 | −0.982 to 0.324 | 0.323 |
Maina et al. (2007) | 10.19 | 3.47 | 16 | 9.63 | 4.08 | 16 | 6.06 | 3.92 | 16 | 12.81 | 4.48 | 16 | 0.935 | −0.582 to 2.452 | 0.227 |
Maina et al. (2010) | 13.96 | 5.69 | 23 | 15.96 | 5.62 | 27 | 13.57 | 5.16 | 23 | 15.48 | 5.54 | 27 | −0.262 | −0.550 to 0.026 | 0.075 |
Martini et al. (2011) | 6.94 | 4.55 | 16 | 7.05 | 3.79 | 19 | 4.50 | 4.07 | 16 | 8.00 | 4.47 | 19 | 0.041 | −0.267 to 0.349 | 0.794 |
Vitriol et al. (2009) | 20.92 | 8.51 | 39 | 26.90 | 9.47 | 40 | 16.56 | 9.02 | 36 | 24.20 | 10.99 | 35 | −0.566 | −0.813 to −0.319 | <0.001 |
–, data not available; HAMD, Hamilton Depression Rating Scale.
Note. Negative signs indicate lower depressive symptom levels (i.e. better outcomes) in the combined antidepressants and STPP treatment condition than in the comparison condition.