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. 2023 Sep 12;11:1227440. doi: 10.3389/fcell.2023.1227440

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Copyright © 2023 Xue, Ran, Li, Wang, Chen and Mao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of BMSC-Exo-derived miR-216a-5p on locomotor performance in SCI rats. Comparison of relative miR-216a-5p expression among BMSC, BMSC-NC, and BMSC-miR groups; 3 biological replicative samples were tested in each group (A). Comparison of relative miR-216a-5p expression among BMSC-Exo, BMSC-NC-Exo, and BMSC-miR-Exo groups; 3 biological replicative samples were tested in each group (B). Comparison of relative miR-216a-5p expression (C) and BBB score (D), representative images of HE staining (E), among the SCI, BMSC-Exo, BMSC-NC-Exo, and BMSC-miR-Exo groups; 6 biological replicative samples were tested in each group, and 24 rats were tested in total among the SCI, BMSC-Exo, BMSC-NC-Exo, and BMSC-miR-Exo groups.