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Effect of BMSC-Exo-derived miR-216a-5p on TLR4/NF-κB pathway in SCI rats. Detection of TLR4, myD88, and NF-κB by Western blot analysis (A) and comparison of TLR4/β-ACTIN (B), myD88/β-ACTIN (C), and p-p65 NF-κB/p65 NF-κB (D), among the SCI, BMSC-Exo, BMSC-NC-Exo, and BMSC-miR-Exo groups. Six biological replicative samples were tested in each group, and 24 rats were tested in total among the SCI, BMSC-Exo, BMSC-NC-Exo, and BMSC-miR-Exo groups.
