Table 1.
Summary of doses, outcome, and febrile responses after aerosol exposure to H5N1
| Animal ID | Weight | Dosea | TTDb | Fever |
|||
|---|---|---|---|---|---|---|---|
| ΔT Maxc | Durationd | Severitye | Ave Elevf | ||||
| 147-19 | 3.9 | 2.14 | 15 | 2.8 | 78.3 | 74.1 | 0.9 |
| 148-19 | 3.8 | 3.07 | 15 | 2.1 | 73.3 | 87.6 | 1.2 |
| 153-19 | 3.2 | 4.26 | 15 | 3.0 | 109.3 | 122.5 | 1.1 |
| 154-19 | 3.2 | 4.21 | 15 | 3.5 | 123.0 | 220.0 | 1.8 |
| 156-19 | 3.8 | 4.70 | 15 | 2.7 | 206.3 | 237.1 | 1.1 |
| 145-19 | 6.4 | 5.04 | 4 | 2.4 | 87.0 | 118.4 | 1.4 |
| 150-19 | 3.1 | 5.06 | 6 | 3.1 | 108.8 | 168.5 | 1.5 |
| 155-19 | 3.2 | 5.16 | 15 | 2.6 | 153.5 | 192.6 | 1.3 |
| 151-19 | 5 | 5.36 | 5 | 2.4 | 43.0 | 50.5 | 1.2 |
| 146-19 | 3.3 | 5.39 | 15 | 2.6 | 100.5 | 110.2 | 1.1 |
| 152-19 | 4.1 | 5.53 | 5 | 3.2 | 77.5 | 121.6 | 1.6 |
a
Dose = inhaled dose, in log10 pfu.
b
TTD = time to death.
c
ΔTmax = maximum deviation from predicted temperatures.
d
Duration = hours of significant temperature deviation from predicted.
e
Severity = sum of significant temperature deviations, adjusted to hours.
f
Ave Elev = average elevation in temperature, the product of dividing Severity by Duration.