| Type of study: randomized controlled trial, including factorial trial and cluster‐randomized, but not cross‐over, design (Y/N/UN) |
| Participants: adults undergoing abdominal surgery, open or laparoscopic (Y/N/UN) |
| Type of intervention: dexmedetomidine administered perioperatively and as the sole difference between the intervention group and the control group(s), or administered perioperatively as part of a factorial trial (Y/N/UN) |
| At least one of the following outcomes (underscore) |
| Dose of rescue opioid Postoperative pain measured by VASa Proportion of participants needing rescue analgesia Time to first rescue analgesia Postoperative sedation Proportion of participants with nausea/vomiting or needing antiemetics Time to first flatus/stool or proportion of participants with delay to first flatus/stool Time to out‐of‐bed mobilization or proportion of participants with delay to out‐of‐bed mobilization |
| INCLUDE only if yes in all 4 categories (Y/N/UN) |
| EXCLUDE and record here the information to be inserted into ‘Table of excluded studies’ |
| Notes |
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