Setting (underscore)

Single‐centre Multi‐centre

Inclusion criteria

Exclusion criteria

Informed consent obtained

Ethical approval (underscore)

obtained not needed not obtained though needed not reported

Aim of study (you may copy and paste from the ‘Objectives’ section)

Design of study (underscore)

2 parallel groups multi‐arm parallel groups cluster‐randomized factorial trial (state 2 × 2, 2 × 3, etc)

Intervention group(s) vs control group(s) (e.g. dexmedetomidine vs morphine plus diclofenac vs placebo)

Outcomes measured (list all outcomes mentioned in the report even if no results reported)

Outcomes reported (list all outcomes when corresponding results are reported in text or in tables/figures)

In tables/figures: In text: Qualitatively: Quantitatively: Outcomes measured, but not reported:

Total duration of study

Notes