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. 2016 Feb 18;2016(2):CD010358. doi: 10.1002/14651858.CD010358.pub2

Jung 2014.

Trial name or title Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
Methods RCT, 4 parallel groups
Participants Number: 120 participants, both genders
Country: Korea
Surgery: not stated, elective
Age: > 65 years
ASA: I to II
Other inclusion criteria: not stated
Exclusion criteria: severe heart disease (New York Heart Association class > III, severe arrhythmia, uncontrolled hypertension or hypotension, hypersensitivity to drugs, cognitive deficiency, dementia or delirium, hepatic or renal impairment, infective disease
Interventions
  • General anaesthesia with sevoflurane (n = 30)


vs
  • General anaesthesia with propofol and remifentanil (n = 30)


vs
  • General anaesthesia with sevoflurane. Infusion of dexmedetomidine (0.4 μg/kg/h) during anaesthesia (n = 30)


vs
  • General anaesthesia with propofol and remifentanil. Infusion of dexmedetomidine (0.4 μg/kg/h) during surgery (n = 30)

Outcomes Recovery characteristics (time to recovery of consciousness (ROC) and recovery)
Bispectral index (BIS) values at ROC and orientation
Ricker sedation‐agitated scale at the postanaesthetic care unit
Safety (vital signs during and after administration of dexmedetomidine)
Starting date May 2013
Contact information Study Chair: Ki Tae Jung, MD, Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University, Gwangju, Korea, 501‐717
Notes Status at clinicaltrials.gov: completed, last verified March 2014, no results posted
Clinical Trials identifier: NCT01851005
Type of surgery not stated ‐ might not be abdominal surgery