Table 3.
Crude and adjusted odds ratios (and 95% confidence intervals) from logistic regression evaluating associations between selected characteristics and post-appendectomy surgical site infection
Crude OR (95% CI) | Adjusted OR (95% CI) | |
---|---|---|
Sex | ||
Male | 1.00 | – |
Female | 0.71 (0.44, 1.16) | – |
Age, for each additional year of age | 0.95 (0.8, 1.01) | 0.94 (0.88, 1.00) |
ASA classification | ||
Class 1 or 2 | 1.00 | 1.00 |
Class 3, 4 or 5 | 3.71 (0.84, 16.41) | 4.39 (0.99, 19.49) |
Hospital size | ||
≤ 200 beds | 1.00 | – |
200–499 beds | 1.27 (0.65, 2.50) | – |
≥ 500 beds | 1.44 (0.74, 2.77) | – |
Type of surgical approach | ||
Open | 1.00 | – |
Laparoscopic | 0.6 (0.24, 1.51) | – |
Duration of surgery, for each additional 30 min | 1.15 (1.00, 1.33) | 1.22 (1.02, 1.46) |
Duration of surgery > 75th centile | 1.31 (0.80, 2.12) | – |
Perioperative antibiotic regimen | ||
Amoxicillin/clavulanic acid | 1.00 | 1.00 |
Cefuroxime plus metronidazole | 0.37 (0.21, 0.65) | 0.34 (0.19, 0.60) |
Timing of administration of first prophylaxis prior to incision, for each additional 30 min | 1.12 (1.03, 1.21) | 1.11 (1.02, 1.20) |