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. 2023 Sep 26;22:158. doi: 10.1186/s12944-023-01915-y

Table 2.

Association between RC and hypertension, T2DM, and their coexistence in NHANES 2005–2018 (N = 17,749)

Unadjusted Adjusted Model 1 Adjusted Model 2 Adjusted Model 3
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Raw data with missing values
 Hypertension 3.829(3.321,4.415)  < 0.001 2.601(2.252,3.004)  < 0.001 2.697(2.317,3.139)  < 0.001 1.068(1.063,1.073)  < 0.001
 T2DM 4.158(3.603,4.798)  < 0.001 3.342(2.817,3.964)  < 0.001 3.557(2.950,4.288)  < 0.001 2.259(1.797,2.838)  < 0.001
 Hypertension &T2DM 4.107(3.478,4.849)  < 0.001 3.449(2.821,4.217)  < 0.001 3.787(3.045,4.710)  < 0.001 2.362(1.834,3.041)  < 0.001
Multiple Imputation based on mice
 Hypertension 3.829(3.321,4.415)  < 0.001 2.601(2.252,3.004)  < 0.001 2.914(2.526,3.362)  < 0.001 1.866(1.594,2.186)  < 0.001
 T2DM 4.158(3.603,4.798)  < 0.001 3.342(2.817,3.964)  < 0.001 3.594(3.002,4.304)  < 0.001 2.466(2.030,2.996)  < 0.001
 Hypertension & T2DM 4.107(3.478,4.849)  < 0.001 3.449(2.821,4.217)  < 0.001 3.900(3.171,4.797)  < 0.001 2.661(2.148,3.297)  < 0.001
Unit replaced with mg/dL
 Hypertension 1.035(1.032,1.039)  < 0.001 1.025(1.021,1.029)  < 0.001 1.026(1.022,1.030)  < 0.001 1.014(1.010,1.019)  < 0.001
 T2DM 1.038(1.034,1.041)  < 0.001 1.032(1.027,1.036)  < 0.001 1.033(1.028,1.038)  < 0.001 1.021(1.015,1.027)  < 0.001
 Hypertension & T2DM 1.037(1.033,1.042)  < 0.001 1.033(1.027,1.038)  < 0.001 1.035(1.029,1.041)  < 0.001 1.022(1.016,1.029)  < 0.001

Notes: Model 1 was adjusted by age and sex; Model 2 was adjusted by age, sex, race, education, marital status, and PIR; Model 3 was additionally adjusted by smoking, alcohol, BMI levels, HEI, DII, and waist

Abbreviations: T2DM Type 2 diabetes, RC Remnant cholesterol, OR Odds ratio, CI Confidence interval