Table 1.
Clinical characteristics of different groups of patients included in the study
| C (n = 15) | DLP (n = 14) | T2D (n = 17) | T2D-DLP (n = 17) | |
|---|---|---|---|---|
| Anthropometric data | ||||
| Gender (F/M) | 3F/2 M | 3F/1 M | 2F/5 M | 8F/9 M |
| Age (years) | 43 ± 8 | 60 ± 11 | 64 1 ± 13 | 58 ± 9 |
| Onset of disease (years) | 0 | 0 | 1 → 10 | 1 → 14 |
| BMI (kg/m2) | 29 ± 7 | 35 ± 2 | 29 ± 4 | 32 ± 5 |
| Metabolic waste products | ||||
| Serum urea (mg/dL) | 24 ± 6 | 32 ± 8 | 35 ± 14 | 33 ± 10 |
| Serum creatinine (mg/dL) | 1 ± 0 | 1 ± 0 | 1 ± 0 | 1 ± 0 |
| Serum uric acid (mg/dL) | 5 ± 2 | 7 ± 2 | 5 ± 2 | 5 ± 1 |
| Serum hemoglobin (g/dL) | 14 ± 1 | 15 ± 1 | 15 ± 1 | 14 ± 1 |
| Erythrocytes (mm3) | 5,040,000 ± 183,847 | 5,210,000 ± 226,274 | 5,152,000 ± 388,361 | 4,913,333 ± 795,831 |
| Platelets (mm3) | 233,666 ± 68,233 | 244,375 ± 164,421 | 193,714 ± 52,392 | 253,316 ± 55,037 |
| Leucocytes (mm3) | 6496 ± 2409 | 10,452 ± 4060 | 7634 ± 2779 | 8399 ± 2302 |
| Monocytes (mm3) | 623 ± 68 | 713 ± 396 | 664 ± 75 | 755 ± 160 |
| Metabolic parameters | ||||
| Fasting plasma glucose (mg/dL) | 80 ± 10 | 88 ± 9 | 152 ± 48a | 144 ± 28a |
| HbA1c (%) | 5 ± 0.6 | 6 ± 0.8 | 7 ± 1.4a | 7 ± 2ª |
| Serum triglycerides (mg/dL) | 104 ± 27 | 212 ± 17a | 125 ± 11 | 167 ± 11a,b |
| Serum cholesterol (mg/dL) | 200 ± 32 | 204 ± 71 | 171 ± 39 | 162 ± 48 |
| HDL cholesterol (mg/dL) | 54 ± 19 | 38 ± 7 | 44 ± 14 | 40 ± 5 |
| LDL cholesterol (mg/dL) | 104 ± 17 | 127 ± 27 | 101 ± 35 | 129 ± 29 |
| TGO (UI/L) | 22 ± 10 | 20 ± 5 | 19 ± 18 | 22 ± 12 |
| TGP (UI/L) | 24 ± 13 | 23 ± 17 | 22 ± 13 | 26 ± 15 |
| Heart function | ||||
| Systolic blood pressure (mmHg) | 113 ± 10 | 152 ± 19a | 132 ± 10ª | 133 ± 15 |
| Diastolic blood pressure (mmHg) | 68 ± 10 | 96 ± 11a | 81 ± 13 | 76 ± 11 |
| Heart rate (bpm) | 71 ± 9 | 93 ± 8 | 94 ± 11 | 84 ± 10 |
Data presented as mean ± SD (one-way ANOVA and Bonferonni)
C control, DLP dyslipidemia, T2D type 2 diabetes, T2D-DLP diabetic dyslipidemia
ap < 0.05 vs C
bp < 0.05 vs T2D