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. 2023 Sep 25;14:271. doi: 10.1186/s13287-023-03471-9

Table 2.

The correlation between SCFAs and cytokine in SFF model system

Cytokine SCFAs
Acetate Propionate Butyrate
r p r p r p
CCL5 0.919 < 0.001 0.860 0.001 0.967 < 0.001
IL-10 0.728 0.017 0.780 0.008 0.749 0.012
IL-17A − 0.929 < 0.001 − 0.839 0.002 − 0.808 0.005
IL-6 − 0.965 < 0.001 − 0.873 < 0.001 − 0.890 < 0.001
IL-1β − 0.723 0.018 − 0.731 0.016 − 0.853 0.002

SCFA short-chain fatty acid, SFF sterile fecal filtrate, CCL5 C–C chemokine ligand 5, IL interleukin