TABLE 2.
Distribution of 9,243 pneumococcal isolates according to MICs of penicillin and cefotaxime in Spain from 1990 to 1996a
| MIC cefotaxime (μg/ml): | No. of strains for which the MIC of penicillin (μg/ml) is:
|
Total no. of strains | |||||||
|---|---|---|---|---|---|---|---|---|---|
| ≤0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | ||
| ≤0.06 | 4,650 | 114 | 21 | 2 | 2 | 0 | 0 | 0 | 4,789 |
| 0.12 | 52 | 175 | 223 | 28 | 1 | 0 | 0 | 0 | 479 |
| 0.25 | 8 | 41 | 282 | 233 | 21 | 1 | 0 | 0 | 586 |
| 0.5 | 6 | 4 | 41 | 451 | 806 | 73 | 0 | 0 | 1,381 |
| 1 | 0 | 0 | 4 | 64 | 1,049 | 652 | 7 | 0 | 1,776 |
| 2 | 0 | 0 | 1 | 0 | 37 | 134 | 22 | 2 | 196 |
| 4 | 0 | 0 | 0 | 1 | 1 | 3 | 16 | 7 | 28 |
| 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 8 |
| Total no. of strains | 4,716 | 334 | 573 | 779 | 1,917 | 863 | 45 | 16 | 9,243 |
Susceptibility categorizations for penicillin and cefotaxime: highly resistant, MIC ≥ 2 μg/ml (both); moderately resistant, 0.12 μg/ml ≤ MIC ≤ 1 μg/ml and MIC = 1 μg/ml, respectively; and susceptible, MIC ≤ 0.06 μg/ml and ≤ MIC ≤ 0.5 μg/ml, respectively.