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. 2023 Sep 26;131(9):097009. doi: 10.1289/EHP11811

Table 1.

Characteristics of the girls in the puberty cohort with PFAS serum measurements, 2004–2014, by study site.

Characteristic Both sites combined (n=704) Greater Cincinnati Area (n=353) San Francisco Bay Area (n=351) p-Valuea
Median BMI% at baseline 66.39 64.89 68.82 0.28
Mean age of pubertal stage [months (mean±SD mean]b
 Thelarche 111.58±14.57 107.09±14.82 116.17±12.79 <0.01
 Pubarche 118.63±17.19 118.12±17.24 119.14±17.16 0.27
 Menarche 147.99±14.48 147.66±14.81 148.27±14.23 0.65
Pubertal stage attained by end of follow-up [n (%)]
 Thelarche 655 (93.04) 331 (93.75) 324 (92.31) 0.72
 Pubarche 633 (89.91) 316 (89.49) 317 (90.31) 0.52
 Menarche 575 (81.67) 263 (74.50) 312 (88.89) <0.01
Median BMI% closest to pubertal stagec
 Thelarche 65.74 65.67 66.28 0.52
 Pubarche 67.26 69.05 64.72 0.70
 Menarche 67.28 68.11 65.83 0.20
Race/ethnicity [n (%)] <0.01
 White 364 (51.70) 215 (61.08) 149 (42.45)
 Asian 46 (6.53) 5 (1.42) 41 (11.68)
 Hispanic 98 (13.92) 14 (3.98) 84 (23.93)
 Black 196 (27.84) 119 (33.52) 77 (21.94)
Maternal age of menarche (y) [n (%)] 0.22
<12 153 (21.73) 71 (20.17) 82 (23.36)
 Between 12 and <14 404 (57.39) 214 (60.51) 190 (54.13)
14 147 (20.88) 68 (19.32) 79 (22.51)
Parent/caregiver education [n (%)] <0.01
 Grade school, some high school, high school grad or GED 98 (13.92) 33 (9.35) 65 (18.52)
 Some college/technical/trade/vocational school or an associate’s degree 226 (32.10) 116 (32.86) 110 (31.34)
 Bachelor’s degree 204 (28.97) 103 (29.18) 101 (28.77)
 Master’s degree or higher 127 (18.03) 83 (23.51) 44 (12.54)
 Missing 49 (6.96) 18 (5.10) 31 (8.83)

Note: Significance declared at p-value 0.05. BMI, body mass index; BMI%, BMI percentile; CDC, Centers for Disease Control and Prevention; GED, General Education Development; PFAS, per- and polyfluoroalkyl substances; y, years.

a

Test of significance of difference in values for Greater Cincinnati Area compared with San Francisco Bay Area; Fisher exact test for categorical variables and Kruskal–Wallis for continuous variables.

b

Of those who were not right-censored.

c

BMI% from CDC 2000 Female BMI-for-age table36; height and weight at closest visit prior to pubertal event.