Brain volume versus genotype in females graphed: a)
HTR2C SNP rs12860460, showing females with genotype and corresponding ACC volume (cc) for controls (green) and for OCD cases (purple); ACC volume decreases by 4.37 cc in controls (with 0, 1, or 2 tested C alleles) and ACC volume increases by 1.08 cc in OCD cases (with 0, 1, or 2 tested C alleles). b)
HTR2C SNP rs12854485, showing females with genotype and corresponding ACC volume (cc) for controls (green) and for OCD cases (purple); ACC volume decreases by 3.26 cc in controls (with 0, 1, or 2 tested G alleles) and ACC volume increases by 1.02 cc in OCD cases (with 0, 1, or 2 tested G alleles). OCD, obsessive-compulsive disorder; ACC, anterior cingulate cortex; cc, cubic centimeters