TABLE 3.
Susceptibilities of 513 yeast isolates from blood cultures to antifungal agents
Antifungal agent | Species | No. of isolates | MIC (μg/ml)a
|
||
---|---|---|---|---|---|
50% | 90% | Range | |||
Amphotericin B | C. albicans | 336 | 0.5 | 0.5 | 0.03–1 |
C. glabrata | 66 | 0.5 | 1 | 0.03–1 | |
C. parapsilosis | 44 | 0.5 | 1 | 0.03–1 | |
C. tropicalis | 35 | 0.5 | 1 | 0.03–1 | |
C. krusei | 11 | 1 | 1 | 0.25–1 | |
Other species | 21 | 0.5 | 1 | 0.06–1 | |
Fluconazole | C. albicans | 336 | 0.5 | 1 | 0.25–4 |
C. glabrata | 66 | 16 | 64 | 1–128 | |
C. parapsilosis | 44 | 1 | 1 | 0.25–16 | |
C. tropicalis | 35 | 2 | 4 | 0.5–128 | |
C. krusei | 11 | 64 | 64 | 64–128 | |
Other species | 21 | 4 | 64 | 0.5–64 | |
Flucytosine | C. albicans | 336 | 0.25 | 0.5 | 0.064–64 |
C. glabrata | 66 | 0.125 | 0.25 | 0.064–16 | |
C. parapsilosis | 44 | 0.125 | 0.5 | 0.064–1 | |
C. tropicalis | 35 | 0.125 | 0.5 | 0.064–64 | |
C. krusei | 11 | 16 | 32 | 16–32 | |
Other species | 21 | 0.125 | 64 | 0.125–64 |
50% and 90%, MICs at which 50 and 90% of isolates, respectively, are inhibited.