Table 4. Statistical models used in association analysis.
| Genes | Models | Genotype | Cases 250 | Controls 250 | OR 95% Cl | χ2 -value | P-value |
|---|---|---|---|---|---|---|---|
| IL17F rs2397084 | Co- | n (% age) | n (% age) | ||||
| Dominant | CC | 32 (13%) | 35 (14%) | - | 3.202 | 0.201 | |
| Model | CT | 160 (64%) | 173 (70%) | ||||
| TT | 58 (23%) | 42 (16%) | |||||
| Homozygous | TT | 58 (23%) | 42 (16%) | 1.496 | |||
| Dominant | CT + CC | 192 (77%) | 208 (84%) | (0.960–2.330) | - | 0.093 | |
| Homozygous | CC | 32 (13%) | 35 (14%) | 0.901 | |||
| Recessive | CT + TT | 218 (87%) | 215 (86%) | (0.538–1.509) | - | 0.793 | |
| Heterozygou | CT | 160 (64%) | 173 (70%) | 0.791 | |||
| s | CC+TT | 90 (36%) | 77 (30%) | (0.549–1.155) | - | 0.255 | |
| Additive | C | 224 (44.8%) | 243 (48.6%) | 0.858 | |||
| T | 276 (45.2%) | 257 (51.4%) | (0.668–1.101) | 0.253 | |||
| IL17F rs11465553 | Co- | AA | 32 (13%) | 48 (18%) | |||
| Dominant | AG | 179 (72%) | 125 (50%) | - | 25.24 | 0.0001 | |
| Model | GG | 39 (16%) | 77 (32%) | ||||
| Homozygous | GG | 39 (16%) | 77 (32%) | 0.415 | |||
| Dominant | AG +AA | 211 (84%) | 173 (68%) | (0.268–0.641) | — | 0.0001 | |
| Homozygous | AA | 32 (13%) | 48 (18%) | 0.617 | |||
| Recessive | GG +AG | 218 (87%) | 202 (82%) | (0.379–1.005) | — | 0.066 | |
| Heterozygou | AG | 179 (72%) | 125(50%) | 1.19 | |||
| s | AA+GG | 71 (28%) | 125 (50%) | (0.790–1.791) | — | 0.466 | |
| Additive | A | 243 (48.6%) | 221 (44.2%) | 1.194 | |||
| G | 257 (51.4%) | 279 (54.8%) | (0.930–1.531) | — | 0.183 | ||
| IL17F Irs763780 | Co- | TT | 79 (31.6%) | 192 (76.8%) | |||
| Dominant | CC | 18 (7.2%) | 17 (6.8%) | - | 111.8 | <0.0001 | |
| Model | CT | 153 (61.2%) | 41 (16.4%) | ||||
| Homozygous | TT | 79 (39%.76) | 192(28.23%) | 0.139 | |||
| Dominant | CT + CC | 171(60.24%) | 58(61.67%) | (0.093–0.027) | - | 0.001 | |
| Homozygous | CC | 18 (16.20%) | 17 (21.08%) | 1.063 | |||
| Recessive | CT + TT | 232 (83.80%) | 233 (78.92%) | (0.534–2.115) | - | 1.00 | |
| Heterozygou | CT | 153 (61.2%) | 41 (16.4%) | 4.193 | |||
| s | CC+TT | 97 38.8%) | 109(83.6%) | (2.70–6.51) | - | 0.0001 | |
| Additive | C | 189(37.8%) | 75 (15%) | 3.444 | |||
| T | 311 (62.2%) | 425 (85%) | (2.539–4.672) | 0.0001 |