Table 2. Biochemical, metabolic indexes and hemodynamic markers of groups higher and smaller Irisin.
| Variable | Higher Irisin Group (HIG) n = 11 | Smaller Irisin Group (SIG) n = 9 |
|---|---|---|
| Fasting insulin (uU/mL) | 9.14 ± 2.09 | 14.26 ± 5.9* |
| Fasting glucose (mmol/l) | 5.18 ± 0.25 | 5.24 ± 0.72 |
| HbA1c: (%) | 5.34 (5.15-5.53) | 5.35 (4.79-5.91) |
| HOMA2-B | 107.03 (90.93-123.13) | 143.03 (87.66-198.39) |
| HOMA2-S | 83.48 ± 23.7 | 58.16 ± 19.24* |
| HOMA2-IR | 1.23 ± 0.27 | 1.81 ± 0.71* |
| QUICKI Index | 0.34 ± 0.02 | 0.31 ± 0.01* |
| TYG Index | 4.69 ± 0.19 | 4.87 ± 0.21* |
| Triglycerides (mmol/l) | 1.43 9 (1.09-1.81) | 2.27 (1.60-2.94)* |
| Total Cholesterol (mmol/l) | 4.64 ± 0.90 | 5.22 ± 1.15 |
| HDL (mmol/l) | 1.05 ± (0.94-1.59) | 1.09 (0.87-1.31) |
| VLDL (mmol/l) | 0.72 ± 0.33 | 1.04 ± 0.40† |
| LDL (mmol/l) | 2.86 ± 0.76 | 3.02 ± 1.04 |
| Systolic pressure (mm/Hg) | 125.82 ± 16.26 | 117.14 ± 12.44 |
| Diastolic pressure (mm/Hg) | 87.09 ± 11.95 | 80.28 ± 5.6 |
HbA1c: glycated hemoglobin; HOMA-B: homeostatic model assessment - beta; HOMA-S: homeostatic model assessment - sensibility; HOMA-IR: homeostatic model assessment - insulin resistance; TYG Index: triglycerides/glucose index; HDL: high density lipoprotein; VLDL: very low density lipoprotein; LDL: low density lipoprotein.
*
significant difference between HIG and SIG (p < 0.05).
†
trend difference between HIG and SIG (p between 0.051 and 0.090). Parametric variables were expressed as the mean ± standard deviation; non-parametric variables were expressed as the median (interquartile range).