Table 2. BMI: body mass index; LDL: low density lipoprotein; HDL: high density lipoprotein; NS: non-significant.

. Comparison of irisin, retinol binding protein-4, adiponectin and inflammatory mediators of the groups according to HbA1c levels

	Group A (HbA1c < 6.5%) n = 68	Group B (HbA1c: 6.5-8%) n = 56	Group C (HbA1c > 8%) n = 56	P (A-B)	P (A-C)
hsCRP (mg/dL)	0.97 ± 1.37	2.97 ± 1.63	3.19 ± 1.72	0.000	0.000
PTX-3 (pg/mL)	256.89 ± 120.27	326.53 ± 107.10	317.83 ± 112.30	0.001	0.005
IL-33 (pg/mL)	5.18 ± 1.14	5.23 ± 0.82	5.37 ± 0.86	0.793	0.325
Irisin (ng/mL)	47.95 ± 19.05	62.61 ± 18.07	62.56 ± 17.23	0.000	0.000
RBP- 4 (mg/mL)	40.35 ± 12.28	54.49 ± 10.71	57.64 ± 15.51	0.000	0.000
Adiponectin (mg/mL)	6.13 ± 2.14	3.61 ± 1.27	3.46 ± 1.30	0.000	0.000

hsCRP: high sensitivity C-reactive protein; PTX-3: pentraxin-3; IL-33: interleukin-33; RBP- 4: retinol binding protein – 4.

There was no difference between Group B and C with regard to these biomarkers.