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. 2021 Mar 19;65(4):479–487. doi: 10.20945/2359-3997000000340

Table 2. Correlations between galanin levels and clinical, metabolic, hormonal and androgen excess parameters.

All patients (n=88) PCOS (n=44) Controls (n=44)
r p a r p b r p b
Age (years) 0.087 0.422 -0.028 0.858 0.149 0.335
BMI (kg/m2) 0.689 <0.001 0.966 <0.001 0.768 <0.001
FPG (mg/dL) 0.017 0.872 0.100 0.519 0.108 0.484
FI (μIU/mL) 0.216 0.043 0.488 <0.001 0.199 0.196
HOMA-IR 0.211 0.048 0.474 <0.001 0.217 0.157
TC (mg/dL) 0.025 0.819 -0.094 0.546 0.252 0.099
HDL(mg/dL) -0.192 0.072 -0.467 <0.001 -0.009 0.953
LDL(mg/dL) -0.063 0.557 -0.114 0.463 0.187 0.224
TG(mg/dL) 0.230 0.031 0.358 <0.001 0.284 0.062
fT(pg/mL) -0.007 0.946 0.652 <0.001 -0.124 0.423
DHEA-SO4 (μg/dL) -0.069 0.520 0.170 0.269 -0.076 0.622
fT3 (pg/mL) -0.102 0.344 0.052 0.738 -0.174 0.260
fT4 (pg/mL) -0.155 0.151 -0.032 0.836 -0.175 0.255
TSH (μIU/mL) -0.017 0.873 0.104 0.503 -0.204 0.185
FSH (μIU/mL) -0.111 0.302 -0.149 0.336 -0.325 0.031
LH (μIU/mL) -0.222 0.038 -0.044 0.776 -0.085 0.584
E2 (pg/mL) 0.089 0.410 -0.101 0.513 0.162 0.295
PRL (μIU/mL) 0.122 0.259 0.200 0.192 0.017 0.913
mFG 0.202 0.059 0.693 <0.001 0.407 0.006
Glypican4 (ng/mL) 0.651 <0.001 0.965 <0.001 0.770 <0.001

BMI: body mass index; FPG: fasting plasma glucose; FI: fasting insulin; HOMA-IR: Homeostasis Model Assessment-Insulin resistance; TC: total cholesterol; HDL: high density lipoprotein; LDL: low density lipoprotein; TG: triglycerides; fT: free testosterone; DHEA-SO4: dehydroepiandrosterone sulphate; fT3-fT4: free thyroxine levels; TSH: thyroid stimulating hormone; FSH: follicle stimulating hormone; LH: luteinizing hormone; E2:estradiol; PRL: prolactin; mFG: modified Ferriman–Gallwey.

a

p value less than 0.05 was considered statistically significant;

b

p value less than 0.025 was considered statistically significant with regard to Bonferroni adjustment.

r: Correlation coefficient;

Spearman's Rank Correlation test.