Table 2. Correlations between galanin levels and clinical, metabolic, hormonal and androgen excess parameters.
All patients (n=88) | PCOS (n=44) | Controls (n=44) | ||||
---|---|---|---|---|---|---|
r | p a † | r | p b † | r | p b † | |
Age (years) | 0.087 | 0.422 | -0.028 | 0.858 | 0.149 | 0.335 |
BMI (kg/m2) | 0.689 | <0.001 | 0.966 | <0.001 | 0.768 | <0.001 |
FPG (mg/dL) | 0.017 | 0.872 | 0.100 | 0.519 | 0.108 | 0.484 |
FI (μIU/mL) | 0.216 | 0.043 | 0.488 | <0.001 | 0.199 | 0.196 |
HOMA-IR | 0.211 | 0.048 | 0.474 | <0.001 | 0.217 | 0.157 |
TC (mg/dL) | 0.025 | 0.819 | -0.094 | 0.546 | 0.252 | 0.099 |
HDL(mg/dL) | -0.192 | 0.072 | -0.467 | <0.001 | -0.009 | 0.953 |
LDL(mg/dL) | -0.063 | 0.557 | -0.114 | 0.463 | 0.187 | 0.224 |
TG(mg/dL) | 0.230 | 0.031 | 0.358 | <0.001 | 0.284 | 0.062 |
fT(pg/mL) | -0.007 | 0.946 | 0.652 | <0.001 | -0.124 | 0.423 |
DHEA-SO4 (μg/dL) | -0.069 | 0.520 | 0.170 | 0.269 | -0.076 | 0.622 |
fT3 (pg/mL) | -0.102 | 0.344 | 0.052 | 0.738 | -0.174 | 0.260 |
fT4 (pg/mL) | -0.155 | 0.151 | -0.032 | 0.836 | -0.175 | 0.255 |
TSH (μIU/mL) | -0.017 | 0.873 | 0.104 | 0.503 | -0.204 | 0.185 |
FSH (μIU/mL) | -0.111 | 0.302 | -0.149 | 0.336 | -0.325 | 0.031 |
LH (μIU/mL) | -0.222 | 0.038 | -0.044 | 0.776 | -0.085 | 0.584 |
E2 (pg/mL) | 0.089 | 0.410 | -0.101 | 0.513 | 0.162 | 0.295 |
PRL (μIU/mL) | 0.122 | 0.259 | 0.200 | 0.192 | 0.017 | 0.913 |
mFG | 0.202 | 0.059 | 0.693 | <0.001 | 0.407 | 0.006 |
Glypican4 (ng/mL) | 0.651 | <0.001 | 0.965 | <0.001 | 0.770 | <0.001 |
BMI: body mass index; FPG: fasting plasma glucose; FI: fasting insulin; HOMA-IR: Homeostasis Model Assessment-Insulin resistance; TC: total cholesterol; HDL: high density lipoprotein; LDL: low density lipoprotein; TG: triglycerides; fT: free testosterone; DHEA-SO4: dehydroepiandrosterone sulphate; fT3-fT4: free thyroxine levels; TSH: thyroid stimulating hormone; FSH: follicle stimulating hormone; LH: luteinizing hormone; E2:estradiol; PRL: prolactin; mFG: modified Ferriman–Gallwey.
p value less than 0.05 was considered statistically significant;
p value less than 0.025 was considered statistically significant with regard to Bonferroni adjustment.
r: Correlation coefficient;
Spearman's Rank Correlation test.