Table 3. Correlations between glypican-4 levels and clinical, metabolic, hormonal and androgen excess parameters.

	All patients (n=88)		PCOS (n=44)		Controls (n=44)
	r	p a †	r	p b †	r	p b †
Age (years)	0.175	0.104	0.057	0.713	0.434	0.003
BMI (kg/m2)	0.971	<0.001	0.999	<0.001	0.999	<0.001
FPG (mg/dL)	0.230	0.031	0.155	0.314	0.242	0.114
FI (μIU/mL)	0.433	<0.001	0.463	0.002	0.231	0.131
HOMA-IR	0.457	<0.001	0.455	0.002	0.281	0.064
TC (mg/dL)	0.095	0.377	-0.110	0.477	0.302	0.046
HDL (mg/dL)	-0.334	<0.001	-0.508	<0.001	0.086	0.581
LDL (mg/dL)	0.099	0.358	-0.120	0.436	0.270	0.077
TG (mg/dL)	0.292	0.006	0.366	0.015	0.111	0.475
fT (pg/mL)	0.348	<0.001	0.631	<0.001	-0.339	0.024
DHEA-SO4	0.036	0.736	0.133	0.388	-0.363	0.015
fT3 (pg/mL)	0.027	0.800	0.101	0.515	-0.263	0.085
fT4 (pg/mL)	-0.065	0.546	-0.065	0.673	-0.154	0.317
TSH (μIU/mL)	0.012	0.911	0.121	0.433	-0.126	0.414
FSH (μIU/mL)	-0.228	0.033	-0.178	0.247	-0.132	0.393
LH (μIU/mL)	0.085	0.433	-0.049	0.753	-0.140	0.365
E2 (pg/mL)	-0.164	0.127	-0.157	0.310	0.067	0.664
PRL (μIU/mL)	0.055	0.613	0.147	0.340	-0.088	0.569
mFG	0.645	<0.001	0.668	<0.001	0.526	<0.001
Galanin (pg/mL)	0.651	<0.001	0.965	<0.001	0.770	<0.001

BMI: body mass index; FPG: fasting plasma glucose; FI: fasting insulin; HOMA-IR: Homeostasis Model Assessment-Insulin resistance; TC: total cholesterol; HDL: high density lipoprotein; LDL: low density lipoprotein; TG: triglycerides; fT: free testosterone; DHEA-SO4: dehydroepiandrosterone sulphate; fT3-fT4: free thyroxine levels; TSH: thyroid stimulating hormone; FSH: follicle stimulating hormone; LH: luteinizing hormone; E2: estradiol; PRL: prolactin; mFG: modified Ferriman–Gallwey.

^ap value less than 0.05 was considered statistically significant;

^bp value less than 0.025 was considered statistically significant with regard to Bonferroni adjustment.

r: Correlation coefficient;

^†Spearman's Rank Correlation test.