Table 3. Cytokines levels according to genotypes considering all the individuals (T2DM patients and controls).
Polymorphism | Cytokine (fg/mL) | p | |
---|---|---|---|
TNF-α (-308 G/A) (rs1800629) | GG (n = 125) | 95 (55) | 0.705 |
GA (n = 38) | 90 (63) | ||
AA (n = 1) | 47.5† | ||
IL-6 (-174 C/G) (rs1800795) | CC (n =10) | 1381 (2892) | 0.361 |
CG (n = 50) | 565 (754) | ||
GG (n = 104) | 674 (770) | ||
IL-10 (-1082 G/A) (rs1800896) | GG (n = 20) | 204 (55) | 0.278 |
GA (n = 73) | 182 (63) | ||
AA (n = 71) | 185 (65) | ||
IL-10 (-819 T/C) (rs1800871) | TT (n = 20) | 214 (136) | 0.215 |
TC (n = 69) | 182 (69) | ||
CC (n = 75) | 193 (55) | ||
IL-10 (-592 A/C) (rs1800872) | AA (n = 21) | 208 (135) | 0.409 |
AC (n = 68) | 182 (68) | ||
CC (n = 75) | 193 (55) |
TNF-α: tumor necrosis factor-alpha; IL-6: interleukin-6; IL-10: interleukin-10.
Cytokine levels: no normal variable; the data are shown as “median (IQR)”.
p < 0.05 was considered statistically significant.
† data only one individual.