Table SM2. Distributions of genotypes and alleles frequencies in T2DM patients and controls.
| Polymorphisms | T2DM (n = 102) (%) | Control (n = 62) (%) | p | |
|---|---|---|---|---|
| TNF-α (-308 G/A) (rs1800629) | Genotypes | |||
| GG | 78 (76.5) | 47 (75.8) | 0.965 | |
| GA | 23 (22.6) | 15 (24.2) | ||
| AA | 1 (0.9) | 0 | ||
| Alleles | ||||
| G | 179 (87.8) | 109 (87.9) | 0.966 | |
| A | 25 (12.2) | 15 (12.1) | ||
| IL-6 (-174 C/G) (rs1800795) | Genotypes | |||
| CC | 7 (6.8) | 3 (4.8) | 0.348 | |
| CG | 26 (25.5) | 24 (38.7) | ||
| GG | 69 (67.7) | 35 (56.5) | ||
| Alleles | ||||
| C | 40 (19.6) | 30 (24.2) | 0.326 | |
| G | 164 (80.4) | 94 (75.8) | ||
| IL-10 (-1082 G/A) (rs1800896) | Genotypes | |||
| GG | 12 (11.8) | 8 (12.9) | 0.864 | |
| GA | 47 (46.1) | 26 (41.9) | ||
| AA | 43 (42.1) | 28 (45.2) | ||
| Alleles | ||||
| G | 71 (34.8) | 42 (33.9) | 0.863 | |
| A | 133 (65.2) | 82 (66.1) | ||
| IL-10 (-819 T/C) (rs1800871) | Genotypes | |||
| TT | 13 (12.8) | 7 (11.3) | 0.674 | |
| TC | 40 (39.2) | 29 (46.8) | ||
| CC | 49 (48.0) | 26 (41.9) | ||
| Alleles | ||||
| T | 66 (32.4) | 43 (34.7) | 0.665 | |
| C | 138 (67.6) | 81 (65.3) | ||
| IL-10 (-592 A/C) (rs1800872) | Genotypes | |||
| AA | 14 (13.7) | 7 (11.3) | 0.742 | |
| AC | 39 (38.3) | 29 (46.8) | ||
| CC | 49 (48.0) | 26 (41.9) | ||
| Alleles | ||||
| A | 67 (32.8) | 43 (34.7) | 0.733 | |
| C | 137 (67.2) | 81 (65.3) | ||
TNF-α: tumor necrosis factor-alpha; IL-6: interleukin-6; IL-10: interleukin-10.
p < 0.05 was considered statistically significant.