TABLE 4.

Therapeutic strategies before and after availability of results of the Strep A OIA: PED patients

Physician outcome	Therapeutic choice before Strep A OIA result	Therapeutic choice after Strep A OIA result	No. (%) of events
			When physician and OIA agree				When physician and OIA disagree
			Physician presumes GABHS		Physician presumes not GABHS		Physician presumes GABHS		Physician presumes not GABHS
			True positivea	False positive	True negative	False negative	True negative	False negative	True positive	False positive
Total			44 (21.6)	2 (1.0)	149 (73.0)	9 (4.4)	34 (47.2)	2 (2.8)	31 (43.1)	5 (6.9)
OIA result does not change therapy	No antibiotic	No antibiotic	0		130	8	7		0
	2 days	2 days	0		2		4		0
	10 days	10 days	25	2	9	1	6	1	2	1
OIA result changes planned 2- or 10-day therapy to no therapy	2 days	No antibiotic	0		4		9		0
	10 days	No antibiotic	0		0		4	1	0
OIA result changes no therapy or 2-day therapy to 10-day therapy	No antibiotic	10 days	4		4				28	4
	2 days	10 days	15				2		1
OIA creates uncertainty	No antibiotic	2 days	0		0		2		0
	10 days	2 days	0		0		0		0

^aStrep A OIA result versus culture result.