Table 3. Recommendations for Cushing’s syndrome screening.
Cushing’s syndrome screening* |
---|
Presence of multiple and progressive features, especially those more specific to Cushing’s** |
Unusual features for age (vertebral osteoporosis, arterial hypertension) |
Pediatric patients with decreasing growth velocity/short stature and weight gain |
Adrenal incidentaloma |
We do not recommend widespread screening for Cushing’s syndrome in other clinical situations (e.g., obesity, diabetes mellitus, hirsutism) without the presence of more specific features of hypercortisolism |
* References: 27,30,31; ** Easy bruising, facial plethora, proximal myopathy/weakness, striae (especially if red or purple and more than 1 cm wide).