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. 2016 Feb 11;60(3):267–286. doi: 10.1590/2359-3997000000174

Table 3. Recommendations for Cushing’s syndrome screening.

Cushing’s syndrome screening*
Presence of multiple and progressive features, especially those more specific to Cushing’s**
Unusual features for age (vertebral osteoporosis, arterial hypertension)
Pediatric patients with decreasing growth velocity/short stature and weight gain
Adrenal incidentaloma
We do not recommend widespread screening for Cushing’s syndrome in other clinical situations (e.g., obesity, diabetes mellitus, hirsutism) without the presence of more specific features of hypercortisolism

* References: 27,30,31; ** Easy bruising, facial plethora, proximal myopathy/weakness, striae (especially if red or purple and more than 1 cm wide).