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. 2016 Feb 11;60(3):190–198. doi: 10.1590/2359-3997000000134

Table 4. Distribution by gender of RAS genotypes and alleles in Chilean subjects with and without metabolic syndrome.

Sex Genotype No MetS MetS Odds ratio, CI (95%) p-value p-value Adjusted*
  rs4340          
Women II 23 (44.2) 20 (37.0) 1.35 (0.62-2.94) 0.55 0.33
  ID 25 (48.1) 19 (35.2) 0.59 (0.27-1.28) 0.24 < 0.01
  DD 4 (7.7) 15 (27.8) 4.62 (1.41-15.04) 0.01 < 0.01
             
  I 71 (68.3) 59 (54.6) 1.79 (1.02-3.13) 0.048  
  D 33 (31.7) 49 (45.4)      
Men II 4 (23.5) 12 (41.4) 0.44 (0.11-1.67) 0.33 0.20
  ID 10 (58.8) 14 (48.3) 0.65 (0.19-2.19) 0.55 0.40
  DD 3 (17.6) 3 (16.3) 0.54 (0.09-3.03) 0.65 0.44
             
  I 18 (52.9) 38 (65.5) 0.59 (0.25-1.41) 0.27  
  D 16 (47.1) 20 (34.5)      
  rs699          
Women TT 6 (11.8) 7 (13.0) 0.89 (0.28-2.87) 1.00 0.95
  CT 25 (49.0) 29 (53.7) 1.21 (0.56-2.59) 0.69 0.89
  CC 20 (39.2) 18 (33.3) 0.79 (0.35-1.72) 0.68 0.66
             
  T 37 (36.3) 43 (39.8) 0.86 (0.49-1.50) 0.67  
  C 65 (63.7) 65 (60.2)      
Men TT 3 (18.8) 4 (13.8) 1.44 (0.27-7.44) 0.68 0.74
  CT 7 (43.8) 14 (48.3) 1.20 (0.35-4.09) 1.00 0.92
  CC 6 (37.5) 11 (37.9) 1.02 (0.29-3.59) 1.00 0.93
  T 13 (40.6) 22 (37.9) 1.12 (0.46-2.71) 0.82  
  C 19 (59.4) 36 (62.1)      
  rs5186          
Women AA 32 (61.5) 30 (55.5) 1.28 (0.59-2.78) 0.55 0.56
  AC 18 (34.6) 19 (43.2) 1.03 (0.46-2.28) 1.00 0.48
  CC 2 (3.9) 5 (9.3) 2.55 (0.47-13.78) 0.43 0.23
  A 82 (78.8) 79 (73.1) 1.37 (0.73-2.58) 0.34  
  C 22 (21.2) 29 (26.9)      
Men AA 5 (31.3) 15 (51.7) 0.42 (0.11-1.53) 0.22 0.22
  AC 10 (62.5) 14 (48.3) 0.56 (0.16-1.95) 0.53 0.20
  CC 1 (6.3) 0 (0.0) NC 0.36 0.15
  A 20 (62.5) 44 (75.9) 0.53 (0.21-1.35) 0.20  
  C 12 (37.5) 14 (24.1)      

MetS: metabolic syndrome; No MetS: no metabolic syndrome. * P-value adjusted for age.