Table 1.
Overview of structure of data collection toolkits developed by H3Africa.
| Toolkit | Protocols | ||||
|---|---|---|---|---|---|
| Core phenotypes | Demographics+ | Smoking exposure± | Drug use# | Dyslipidemia# | CVD∗ Core# |
| Anthropometrics+ | Smoking status# | Medication log+ | Cancer core+ | HIV core# | |
| Blood pressure# | Alcohol exposure− | Diabetes history+ | Kidney disease core# | Infectious disease core+ | |
| Urine results# | Alcohol use# | Asthma− | Stroke history core# | ||
|
| |||||
| Environmental factors | Household characteristics+ | Sanitation+ | Occupational exposures# | Personal care products# | |
| Water resource+ | Occupational history# | Air contaminants# | |||
|
| |||||
| Lifestyle factors | Physical activity# | Dietary supplements# | Diet+ | Caffeine intake# | Sleep habits# |
|
| |||||
| General medical history | Vaccinations# | Current pregnancy status± | Last pregnancy outcome± | ||
| Allergies+ | Pregnancy history± | Medical history± | |||
|
| |||||
| Family history | Family composition± | Family history± | Family history of traumatic life events± | ||
|
| |||||
| Cardiovascular disease | Angina# | Congestive heart failure# | Cardiac blood flow measurements± | ||
| Heart attack# | Thyroid disease# | Cardiovascular disease blood biomarkers± | |||
|
| |||||
| Stroke | Stroke characterisation± | Prestroke risk reduction strategies± | Poststroke risk reduction strategies± | ||
|
| |||||
| Cancer | Cancer prognosis and treatment+ | Cancer screenings# | Cancer family history± | ||
|
| |||||
| Kidney disease | Kidney treatment status# | Kidney function assay# | Complete blood cell count | ||
|
| |||||
| Rare and developmental disorders | Biological parents and grandparents± | Developmental milestones± | Developmental disorders± | Rare disorders± | |
| Birth history± | Neurodevelopmental assessment± | Epilepsy screener# | |||
|
| |||||
| Infectious diseases | Malaria exposure and treatment± | Trypanosomiasis signs and symptoms+ | TB signs and symptoms± | HIV treatment± | Liver function assay# |
| Malaria testing# | TB history+ | Sexual behaviour# | CD4 count and percentage# | HIV signs and symptoms+ | |
| Malaria signs and symptoms+ | TB testing# | HIV exposure± | Quantitative viral load# | STDs± | |
| Trypanosomiasis testing# | Current TB+ | HIV detection test# | Complete blood cell count# | STD signs and symptoms+ | |
∗ CVD: cardiovascular disease; HIV: human immunodeficiency virus; TB: tuberculosis; STD: sexually transmitted disease; +adapted protocols; ±novel protocols; #existing protocols.