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. 2023 Aug 28;8(10):1911–1919. doi: 10.1038/s41564-023-01461-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, Comparison of mean K13 622I mutation prevalence (P = 0.03, unpaired Student’s t-test, two-tailed) between pfhrp2/3 double (n = 119) and pfhrp2/3 non-deleted (n = 223) parasite populations by district across three regions in Ethiopia. b, Relationship between pfhrp2/3 double-deleted parasite prevalence and K13 622I mutation prevalence by district. Prevalence estimates are weighted (see Supplementary Table 2). Orange points represent districts where parasites harbouring both pfhrp2/3 deletions and K13 622I mutations are observed. The boxplot centre lines in a show the median value, the upper and lower bounds show the 25th and 75th quantiles, respectively, and the upper and lower whiskers show the largest and smallest values, respectively.