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. 2023 Sep 26;14:5995. doi: 10.1038/s41467-023-41608-9

Fig. 7. Evaluation of the healing of small full-thickness wounds treated with ECM scaffolds.

Fig. 7

a Workflow for evaluating skin wound healing. b The surgical process for skin excisional wound model of Ctrl_SW and ECM_SW group. c Representative H&E images of Ctrl_SW and ECM_SW samples. d Histologic quantification of de novo HFs on POD28 (Data are presented as mean ± SD, n = 5 biologically independent samples, two-tailed t-test, ****p = 0.000001). e The anatomical structure of samples. f Spatial feature plot showing the expression of Cd3d (marker gene of T cells) and Crabp1 (marker gene of papillary fibroblasts) in ST profile and corresponding quantitative analysis. p value: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.