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Stability study of optimized oral 250 mg Ciprofloxacin chewable tablet formulation (F-9).
| Evaluation parameters | Initial | 3rd Month | 6th Month |
|---|---|---|---|
| Appearance | Complies | Complies | Complies |
| Drug content (%) | 99.61 | 99.21 | 99.18 |
| Disintegration time (min) | 0.65 | 0.45 | 0.40 |
| Hardness (N) | 79–110 | 76–94 | 68–78 |
| Dissolution after 30 min (%) | 99.30 | 99.42 | 98.66 |
| Taste | No bitterness | No bitterness | No bitterness |
