. 2023 Sep 26;13:16122. doi: 10.1038/s41598-023-43171-1

Table 1.

Echocardiographic follow-up.

	Week 6			Week 12
	Sham (n = 8)	AB_LVH (n = 8)	AB_HF (n = 5)	Sham (n = 8)	AB_LVH (n = 8)	AB_HF (n = 5)
Body weight, g	460 ± 13	480 ± 9	450 ± 15	549 ± 14	576 ± 12	543 ± 23
Heart rate, beats/min	360 ± 9	349 ± 19	365 ± 16	356 ± 14	353 ± 8	340 ± 13
LV AWT_d, mm	1.92 ± 0.07	2.55 ± 0.10*	2.69 ± 0.11*	1.99 ± 0.06	2.65 ± 0.05*	2.78 ± 0.06*
LV AWT_s, mm	3.44 ± 0.08	4.50 ± 0.21*	3.84 ± 0.12^#	3.57 ± 0.11	4.25 ± 0.12*	3.92 ± 0.09
LVEDD, mm	8.05 ± 0.16	8.56 ± 0.14	8.71 ± 0.27	8.32 ± 0.13	8.87 ± 0.15	9.93 ± 0.46*^,#
LVESD, mm	4.68 ± 0.19	4.97 ± 0.20	6.14 ± 0.45*^,#	4.83 ± 0.12	5.53 ± 0.26	7.59 ± 0.60*^,#
LV PWT_d, mm	2.00 ± 0.08	2.73 ± 0.09*	2.60 ± 0.12*	2.00 ± 0.07	2.50 ± 0.05*	2.46 ± 0.11*
LV PWT_s, mm	3.24 ± 0.08	4.24 ± 0.10*	3.53 ± 0.21^#	3.19 ± 0.10	4.13 ± 0.06*	3.26 ± 0.17^#
LV mass, mg	1.25 ± 0.03	2.11 ± 0.07*	2.15 ± 0.10*	1.34 ± 0.04	2.15 ± 0.07*	2.65 ± 0.15*^,#
LVEDV, µl	460 ± 14	518 ± 27	551 ± 48	511 ± 25	572 ± 25	734 ± 80*^,#
LVESV, µl	202 ± 14	243 ± 21	369 ± 52*^,#	211 ± 10	307 ± 21	605 ± 69*^,#
SV, µl	258 ± 12	275 ± 26	182 ± 16^#	300 ± 19	265 ± 15	130 ± 20*^,#
CO, ml/min	97.9 ± 13.0	93.2 ± 5.7	65.9 ± 4.9	106.8 ± 7.9	93.8 ± 6.0	43.1 ± 5.8*^,#
Ejection fraction, %	56 ± 2	53 ± 3	34 ± 5*^,#	59 ± 2	47 ± 2*	18 ± 3*^,#

LV left ventricular, AWT_d anterior wall thickness in diastole, AWT_s anterior wall thickness in systole, LVEDD LV end-diastolic diameter, LVESD LV end-systolic diameter, PWT_d LV posterior wall thickness in diastole, PWT_s LV posterior wall thickness in systole, LVEDV LV end-diastolic volume, LVESV LV end-systolic volume, SV stroke volume, CO cardiac output. The sample numbers are indicated in the table. Depending on the distribution of the datasets, one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test or Kruskal–Wallis test followed by Dunn’s post hoc test was carried out. *P < 0.05 vs. Sham. ^#P < 0.05 vs. AB_LVH.